Blood Type Inheritance Calculator

Predict a child's possible blood types from both parents.

Free blood type inheritance calculator — enter both parents' ABO and Rh blood types to see the possible blood types a child could have and their probabilities. Runs entirely in your browser, nothing is uploaded. It runs free in your browser on Gera Tools, with nothing uploaded.

Last updated Source: Gera Tools

How is blood type inherited?

ABO blood type comes from two alleles, one from each parent, chosen from A, B and O. A and B are co-dominant and O is recessive, so an A parent may secretly carry an O allele. The Rh factor is inherited separately, with positive dominant over negative.

Predict a child’s blood type

Enter both parents’ ABO group and Rh factor, and this calculator shows every blood type a child could inherit along with an approximate probability for each. It is a teaching tool for ABO and Rh genetics.

How it works

Each ABO phenotype maps to its possible genotypes — for example type A is either AA or AO. The calculator forms a Punnett-square cross of every parent genotype combination, tallies the child phenotypes, and assumes each parental genotype is equally likely (since a hidden recessive O can’t be seen without a test). It does the same for Rh, treating a positive parent as equally likely ++ or +−, then multiplies the ABO and Rh probabilities together for the full blood type.

Example

Parent 1 is A+ and Parent 2 is B+. Both could carry an O allele, so the ABO cross can yield A, B, AB or O, and Rh can be + or −:

Possible child typeApprox. probability
AB+highest band
A+ / B+moderate
O+lower
any − typesmaller (needs both Rh parents to carry −)

Because genotypes are assumed equally likely, the percentages are estimates. This is educational only — not a paternity or medical test — and runs entirely in your browser.

ABO genetics explained

The ABO blood group system is controlled by a single gene with three common alleles: I^A (A), I^B (B), and i (O). Every person inherits one allele from each parent, producing six possible genotypes that map to four blood types:

GenotypeBlood typeNotes
I^A I^AAHomozygous A; can only pass A
I^A iACarries a hidden O allele
I^B I^BBHomozygous B; can only pass B
I^B iBCarries a hidden O allele
I^A I^BABCo-dominant; passes either A or B
iiOHomozygous recessive; can only pass O

Because I^A and I^B are co-dominant (neither is dominant over the other), a person with both alleles expresses both A and B antigens, giving blood type AB. The i allele is recessive to both, so blood type O appears only when both alleles are i.

Rh factor inheritance

The Rh factor (D antigen) is controlled by the RHD gene. The RhD positive allele (D) is dominant over RhD negative (d):

  • A Rh-positive parent can be DD (homozygous) or Dd (heterozygous).
  • A Rh-negative parent is always dd.
  • Two Rh-positive parents who are both heterozygous (Dd × Dd) have a 25% chance of producing an Rh-negative child.

Without genetic testing, a Rh-positive person’s exact genotype is unknown, so the calculator assumes equal probability of DD and Dd. This is an approximation — in populations where Rh negativity is rare, most Rh-positive people are DD, which would shift the probability of a negative child downward.

Clinical importance of blood type matching

Blood type compatibility matters in several medical contexts:

  • Blood transfusions — the ABO and Rh antigens are the most immunologically significant. Transfusing incompatible blood can cause a haemolytic reaction, which is potentially life-threatening. Type O-negative is the “universal donor” for red cells in emergencies because it lacks both A, B, and D antigens.
  • Pregnancy (Rh incompatibility) — if a Rh-negative mother carries a Rh-positive baby, fetal red cells can cross the placenta and sensitise the mother’s immune system. In subsequent pregnancies with a Rh-positive baby, the mother’s antibodies can cross back and destroy fetal red cells (haemolytic disease of the fetus and newborn). Anti-D immunoglobulin given during pregnancy prevents sensitisation.
  • Organ transplantation — ABO compatibility is required for solid organ transplants; mismatched transplants face hyperacute rejection.