Maximum allowable blood loss
Maximum allowable blood loss (MABL) is the volume of blood a patient can lose intraoperatively before their haemoglobin falls to a predefined floor that triggers transfusion. Calculating it in advance lets the anaesthetic and surgical team plan blood availability and cell salvage rather than react to unexpected bleeding.
How it works
The standard average-method formula is:
EBV = weight (kg) x coefficient (mL/kg)
MABL = EBV x (Hi - Hf) / Hi
where Hi is the initial (starting) haemoglobin and Hf is the lowest acceptable haemoglobin. The same equation works with haematocrit in place of haemoglobin. The coefficient depends on patient type, for example about 70 mL/kg for an adult male and 65 mL/kg for an adult female.
Tips and notes
Choose the lowest acceptable haemoglobin based on the patient’s comorbidity and the operation, not a single universal trigger. MABL assumes blood is replaced isovolaemically and the haemoglobin falls linearly, which is a simplification; ongoing rapid bleeding can overshoot it. Treat MABL as a planning threshold and always integrate haemodynamics, point-of-care testing, and clinical judgement.